Recent publications

https://www.ncbi.nlm.nih.gov/pubmed/?term=schmidt+hhhw%5BAuthor%5D

Casas AI, Geuss E, Kleikers PWM, Mencl S, Herrmann AM, Buendia I, Egea J, Meuth SG, Lopez MG, Kleinschnitz C, Schmidt HHHW (2017) NOX4-dependent neuronal autotoxicity and blood-brain barrier breakdown explain the superior sensitivity of the brain to ischemic damage. Proc. Natl. Acad. Sci. U.S.A. 114: 12315–12320. Doi: https://doi.org/10.1073/pnas.1705034114

Langhauser F, Casas AI, Dao VTV, Guney E, Menche J, Geuss E, Kleikers PWM, López MG, Barabási AL, Kleinschnitz C, Schmidt HHHW (2018) A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection. NPJ Sys Biol Appl (nature) 4:8. Doi: https://doi.org/10.1038/s41540-017-0039-7

Aguirre-Plans J, Piñero J, Menche J, Sanz F, Furlong LI, Schmidt HHHW, Oliva B, Guney E. (2018) Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology. Pharmaceuticals (Basel) 11(3). pii: E61. Doi: https://doi.org/10.3390/ph11030061

Larsen S, Röttger R, Schmidt H, Baumbach J (2018) E. coli gene regulatory networks are inconsistent with gene expression data. Nucleic Acids Res. NAR-01584-N-2018.R2. Doi: https://doi.org/10.1093/nar/gky1176

Ana I. Casas, Pamela W.M. Kleikers, Eva Geuss, Friederike Langhauser, Thure Adler, Dirk H. Busch, Valerie Gailus-Durner, Martin Hrabê de Angelis, Javier Egea, Manuela G. Lopez, Christoph Kleinschnitz, Harald H.H.W. Schmidt (2019). Calcium-dependent reactive oxygen formation and blood-brain barrier breakdown by NOX5 limits post-reperfusion benefit in stroke. Journal of Clinical Investigation (JCI) Doi: https://doi.org/10.1172/JCI124283

Ana I. Casas, Ahmed A. Hassan, Simon J. Larsen, Vanessa Gomez-Rangel, Mahmoud Elbatreek, Pamela W. M. Kleikers, Emre Guney, Javier Egea, Manuela G. López, Jan Baumbach, Harald H.H.W. Schmidt (2019). From single drug targets to synergistic network pharmacology in ischemic stroke. Proc. Natl. Acad. Sci. U.S.A (PNAS). Doi: https://doi.org/10.1073/pnas.1820799116